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Recent Product Newsletters Cat # PGE 1: ELISA kit for measuring PGE2 in biological samples: $247 This competitive ELISA kit is for determination of PGE2 (Prostaglandin E2) levels in biological samples. The specificity of the PGE2 ELISA was investigated using authentic PGE2 and fatty acids which, based on their structure, might be anticipated to compete with PGE2 for binding to antibodies against PGE2. The anti- PGE2 antibody showed virtually no cross-reactivity with other tested eicosanoids (see Table 1). Prostaglandin E2 (PGE2) is a naturally occurring cyclooxygenase metabolite of the arachidonic acid cascade that mediates many physiological processes1. Upon activation of the AA pathway, PGE2 is synthesized de novo and released into the extracellular space where it acts as a regulator of systemic blood pressure due to either vasopressor or vasodepressor effects based on its interaction with four distinct receptors2. PGE2 is also involved in turmorigenesis and inflammation through activation of Wnt and PPAR signaling pathways3,4,5 and has been shown to regulate hematopoietic stem and progenitor cell function5. Each kit can be used for triplicate analyses of up to 24 samples contains using a 96 well plate format, and contains a vial of PGE2 standard, a vial of PGE2 -conjugated horseradish peroxidase (HRP), and buffers for sample and HRP dilutions, and plate washing. Cat # PGE 11 11: 2X ELISA kits for measuring PGE2 in biological samples: 2X $241.50 = $483 Cat # PGE 21: 5X ELISA kits for measuring PGE2 in biological samples: 5X $219.60 = $1098 Cat # PGE 101: 10X ELISA kits for measuring PGE2 in biological samples: 10X $205 = $2053 NOVEL HYPERTENSION/STROKE BIOMARKERS AND DRUG DEVELOPMENT PRODUCTS   LICENSING OF OUR PATENTED TECHNOLOGIES

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